Weight Loss Drug Mounjaro May Slow Breast Cancer Growth in Mice, Early Study Finds

By 
Dr Amit Kumar Singh
 on 
Jul 25, 2025
 • 
5
 min read

The active ingredient in the popular weight loss and diabetes injection Mounjaro has been found to slow the growth of obesity-related breast cancer in mice, according to new research.

The preliminary findings, presented at the Endocrine Society’s annual conference, suggest that the drug, tirzepatide, could have benefits beyond weight management.

Obesity is a significant public health issue in the UK and is a known risk factor for several types of cancer, including breast cancer. While losing weight has been shown to improve cancer outcomes, many people find it difficult to achieve through traditional methods alone.

Lead study author Amanda Kucinskas, a researcher at the University of Michigan, said, "While it is very preliminary data, our studies in mice suggest that these new anti-obesity drugs may be a way to reduce obesity-associated breast cancer risk or improve outcomes.”

In the study, researchers used a mouse model to investigate the drug's effect. After being fed a high-fat diet to induce obesity, the mice were given either tirzepatide or a placebo.

The results showed that mice treated with the drug lost around 20% of their body weight and body fat, a figure similar to the weight loss seen in humans using the medication. More significantly, the drug also reduced the volume of breast cancer tumours compared to the placebo group. Researchers noted a direct correlation between lower body weight and smaller tumour size at the end of the study.

Scientists are now conducting further studies to understand if the drug has a direct anti-cancer effect or if the tumour reduction is purely a result of the weight loss.

The drug at the centre of this research, tirzepatide, is marketed as Mounjaro in the UK. It is currently available on the NHS for treating type 2 diabetes and can be obtained privately for weight loss.

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